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姓名:郅晓燕 |
学科:植物保护 |
单位:山西农业大学植物保护学院 |
地址:山西省晋中市太谷区铭贤南路1号 |
邮编:030801 |
邮箱:zhi15107022@163.com |
一、个人简介
郅晓燕,女,中共党员,1987年生,博士,副教授。现任职于山西农业大学植物保护学院从事农药学相关教学科研工作。山西省“三晋英才”青年优秀人才,山西农业大学“晋农新秀”入选者。
二、学习工作简历
学习简历
2011.09—2016.06 西北农林科技大学,理学院,化学生物学专业,硕博连读;
2007.09—2011.06 西北农林科技大学,理学院,应用化学专业,本科。
工作简历
2020.06—今 山西农业大学,植物保护学院,副教授;
2018.12—2020.05 山西农业大学,农学院,副教授;
2016.06—2018.11 山西农业大学,农学院,讲师。
三、研究方向
1.天然倍半萜类农用活性物质挖掘及结构优化;
2.特色农用植物资源中活性成分鉴定及高附加值开发。
四、教学科研概述
教学上,主讲《农药残留与检测》、《农田鼠害》及《农药生物测定》等课程。已指导本科生及研究生三十余人。
五、教学科研项目
1.山西省基础研究计划面上项目,202103021224121,2022.01-2024.12,结题,主持;
2.山西省高等学校科技创新基金,2019L0403,2019.07-2021.07,结题,主持;
3.国家自然科学基金青年项目,21702129,2018.01-2020.12,结题,主持;
4.农业部西北黄土高原作物有害生物综合治理重点实验室开放基金,KFJJ20180104,2018.04-2020.04,结题,主持。
5.山西农业大学科技创新基金,2016YJ09,2017.07-2020.07,结题,主持。
六、代表性论文
[1]Zhi XY†, Shi HC†, Yuan X, He MT, Li HW, Guo YQ, Cao H, Yang C*. Natural biphenyl-type neolignans as resources of pesticide candidates: Assembly, insecticidal potency, and cytotoxicity of honokiol/magnolol analogues of isoxazoline hybridization via [3+2] dipolar cycloaddition.J. Agric. Food Chem., 2025, 73, 3930–3941.
[2]Zhi XY†, Hu Q†, Duan JQ, He MT, Zheng ZZ, Liang J, Yang C*. Assembly of thioether analogs from 2-mercaptobenzoxazole-fused honokioland heterocyclic scaffolds and evaluation of their agrochemical potential.Pest Manag. Sci., 2025, 81, 3654–3664.
[3]Yang C*, Yuan X, Li HW, Zhang XY, Kang HT, Duan NR, Hao XJ, Zhao XJ,Zhi XY*. Utilization of natural coumarin resources for developing fungicide candidates: Diversity-Oriented structural design, synthesis, and biological assessment of novel osthole derivatives.J. Agric. Food Chem.,2025,73, 26645–26657.
[4]Zhi XY, Liu Y, Li HW, Zheng ZZ, Yang C*.Optimisation of natural neolignan as pesticide candidates: semisynthesis and insecticidal potential of honokiol derivatives bearing dual phenyl-urea/-thiourea moieties.Nat. Prod. Res., 2025, 1–9.
[5]Zhi XY†, Liu Y†, Liang J, Yuan X, Shi HC, Duan JQ, He MT, Wang Y, Cao H*, Yang C*. Novel pesticide candidates inspired by natural neolignan: Preparation and insecticidal investigation of honokiol analogs containing 2‑aminobenzoxazole-fused core scaffold.J. Agric. Food Chem., 2024, 72, 20805–20815.
[6]Zhi XY*, Zhang Y, Li YF, Liu Y, Niu WP, Zhang CR, Cao H, Hao XJ*, Yang C*. Discovery of natural sesquiterpene lactone 1‑O‑acetylbritannilactone analogues bearing oxadiazole, triazole, or imidazole scaffolds for the development of new fungicidal candidates.J. Agric. Food Chem., 2023, 71, 11680–11691.
[7] Yang C*, Li Y, Zhang Y, Hu Q, Liu Y, Li YF, Shi HC, Song LL, Cao H, Hao XJ,Zhi XY*. Natural sesquiterpene lactone as source of discovery of novel fungicidal candidates: Structural modification and antifungal activity evaluation of xanthatin derived fromXanthium strumariumL.J. Agric. Food Chem.,2023,71, 11239–11251.
[8]Zhi XY†, Song LL†, Liang J, Wei SQ, Li Y, Zhang Y, Hao XJ, Cao H, Yang C*. Synthesis and in vitro antifungal activity of new Michael-type amino derivatives of xanthatin, a natural sesquiterpene lactone fromXanthium strumariumL.Bioorg. Med. Chem. Lett., 2022, 55: 128481.
[9]Zhi XY, Jiang LY, Li T, Song LL, Wang Y, Cao H,Yang C*. Semisynthesis and insecticidal bioactivities of benzoxazole and benzoxazolone derivatives of honokiol, a naturally occurring neolignan derived fromMagnolia officinalis.Bioorg. Med. Chem. Lett., 2020, 30: 127086.
[10]Zhi XY*, Jiang LY, Li T, Song LL, Wu LJ, Cao H, Yang C*. Natural product-based semisynthesis and biological evaluation of thiol/amino-Michael adducts of xanthatin derived fromXanthium strumariumas potential pesticidal agents.Bioorg. Chem., 2020, 97: 103696.
七、发明专利
[1]氮杂取代苍耳亭或氯代苍耳亭类衍生物及其应用,ZL2023102617823。
[2] 13-氨基苍耳亭类衍生物及其制备方法和应用,ZL201910754845.2。
[3]苍耳亭硫醚类和亚胺类衍生物及其制备方法和应用,ZL201910756336.3。
[4]含异恶唑啉结构的苍耳亭类衍生物及其制备方法与应用,CN2025109199682。